Figure 3 illustrated that CM CD8+ cells and cytotoxic T cells (Tc1) (CD8+CXCR5−CXCR3+CXCR4−) were significantly increased in patients with uterine leiomyoma compared with healthy controls; while Tc17 cells (CD8+CXCR5−CXCR3+CXCR4−) were decreased. This evidence concerns the gene CXCR4 and Uterine leiomyoma.