Given regulatory T (Treg; CD4+CD25+CD127−), helper T (Th; CD3+CD4+CXCR5−), and follicular helper T (Tfh; CD3+CD4+CXCR5+) cells are all differentiated from the naïve CD4+ T cells [15], we further compared the distribution of these cells between patients with uterine leiomyoma and healthy controls. This evidence concerns the gene CXCR5 and Uterine leiomyoma.