In order to test if the observed effects could be extended to other cell lines, we tested the ccRCC cell lines 786-O (Fig. 5a–c), RCC4 (Fig. 5d–f), A498 (Fig. 5g–i) as well as CAKI 1 (Fig. 5j–l). This evidence concerns the gene SLC49A4 and nonpapillary renal cell carcinoma.