Kuramochi xenografts treated with ALM201 had decreased CD31+ blood vessels (Fig. 4d), in line with our previous studies with recombinant FKBPL and AD-01.21,24 Furthermore, the in vivo gold standard limiting dilution assay clearly demonstrated that ALM201 significantly decreased the tumour-initiating potential by ten-fold in Kuramochi xenografts (Fig. 4f). Here, PECAM1 is linked to neoplasm.