Hoxb8 mutant mice were earlier detected of compulsive grooming and hair removal (trichotillomania) resembling the obsessive-compulsive disorder (OCD) in humans, and this distinct behavior was attributed to Hoxb8 mutant microglia [102], which were recently found to cause corticostriatal circuit defects in mutant mice [103]. The gene discussed is HOXB8; the disease is trichotillomania.