MTOR and neoplasm: Based on the quantitative data as well as the landscape masks provided by Spa-RQ analysis, we observed a phenotype of stromal MAPK signature in conjunction with tumour-specific mTOR signalling, in both ‘MAPK/mTOR’ (ASC_12, 13) and ‘Null’ (ASC_5) signature ASCs (Fig. 4a,b).