Furthermore, the autophagy adaptor p62/SQSTM, which is also targeted for degradation by autophagy, was reduced in quantity in USP18C61A/C61A MEFs relative to wild-type MEFs at baseline and was further degraded following Listeria infection; this degradation could be partially but not completely halted by Bafilomycin A treatment (Fig. 5c). This evidence concerns the gene SQSTM1 and listeriosis.