NFKB1 and breast carcinoma: This study uses a high-power infrared laser (at 1064 nm) to measure the radio sensitivity of 4T1 breast carcinoma cell lines treated by a naturally occurring compound, 2-Dodecyl-6-methoxycyclohexa-2, 5-diene-1, 4-dione (DMDD) extracted from the root of Averrhoa carambola L. Studies have shown that DMDD induces apoptosis of various human breast cancer cells through production of intracellular reactive oxygen species (ROS) and inhibition of NF-κB activation21.