As presented in Fig. 2b, we found the combination of the two hemibodies to stimulate donor T cells to secrete interferon-γ (IFN-γ), interleukin-2 (IL-2), and to lyse tumor cells at half-maximal effective concentrations (EC50) of 290, 340, and 260 pM, respectively. The gene discussed is IFNG; the disease is neoplasm.