In addition, vascular embolism, reduced vascular density and occluded migration passages in this starvation therapy also hamper the infiltrations of macrophages (CD11b+F480+), dendritic cells (DC, Cd11b-CD11c+) and leukocytes cells (CD45+) in tumor (Fig. 7i and Supplementary Fig. 21)36. The gene discussed is ITGAX; the disease is neoplasm.