ZFYVE27 and epilepsy: Meanwhile, quantitative immunofluorescence analysis revealed only weak green staining for protrudin in the hippocampus of PTZ-kindled mice, whereas strong staining for protrudin was detected in controls (Control, 1.636 ± 0.196; Epilepsy, 1.224 ± 0.343; P = 0.004) (Fig. 1d).