EP300 and acute myeloid leukemia: ChIP-seq analysis of the inv(3) MOLM-1 AML cell line defined a putative enhancer element within this translocated 18 kb noncoding sequence owing to its significant enrichment for the p300 transcriptional coactivator (EP300) and for the H3K27ac, H3K4me3 and H3K4me1 histone marks.