CD68 and neoplasm: By multivariate analysis with the variables including tumor diameter, TNM stage, and grade, we found that CD47high/CD68+ Mhigh (HR = 2.126; p = 0.006), CD47high/CD163+ M2high (HR = 1.873; p = 0.035), CD47low/CD68+ Mlow (HR = 0.47; p = 0.01), and CD47low/CD163+ M2low (HR = 0.376; p = 0.002) were independent prognostic factors for OS (Additional file 1: Table S3).