When both anti-CD47 mAb and anti-PD-L1 mAb were applied, the inhibition of tumor growth was synergistic compared to either anti-CD47 or anti-PD-L1 alone, as assessed by the tumor volume (p < 0.001; p = 0.006) and weight (p < 0.001; p = 0.005; Fig. 6d). The gene discussed is CD47; the disease is neoplasm.