Malaria associated inflammation as represented by CRP (geometric mean CRP, mg/l, (n) 1.3 [95% CI 1.0:1.7] (142) without parasitaemia; 9.2 [7.8:10.9] (169) with parasitaemia; relative risk: 1.97 [1.66:2.29], P < 0.001) upregulates hepcidin [8, 16]. The gene discussed is CRP; the disease is malaria.