However, knockout or overexpression of Caprin1 alone had no obvious effect on the DNA synthesis (Additional file 1: Figure S10A and B), cell cycle progression (Additional file 1: Fig. S10C and D), cell growth (Additional file 1: Figure S10E and F) and migration (Additional file 1: Figure S10G and H) in prostate cancer cells. Here, CAPRIN1 is linked to Familial prostate cancer.