TNF and metabolic dysfunction-associated steatotic liver disease: In NAFLD, the secretion of adipokines shifts to an abnormal pattern with a decreased secretion of adiponectin [18] and an increase in the levels of resistin, leptin and proinflammatory cytokines such as tumor necrosis factor alpha (TNF-α), interleukins (IL-1, IL-6) and monocyte chemoattractant protein-1 (MCP-1), which promote hepatic insulin resistance [19].