We also document two new cases of complete TAL deficiency due to (a) C→T variation at nucleotide position 610 of the TAL cDNA which resulted in amino acid S187F substitution in a child born to consanguineous parents of Turkish origin and diagnosed with liver cirrhosis at 7 months of age; and (b) insertion of a guanine (G) nucleotide at cDNA base position 103 which resulted in frame‐shifting and termination codon at amino acid position 81 in a child transplanted for congenital liver fibrosis (CLF) at 13 years of age in the United States. Here, TALDO1 is linked to cirrhosis of liver.