PRKAA1 and diabetes mellitus: In order to explore the effect of AMPK on apoptosis of gastric smooth muscle cells in DGP rats and the underlying mechanism, we first prepared a rat model of DGP diabetes, and observed the apoptosis of gastric smooth muscle cells in DGP rats, the results showed that the apoptosis rate of gastric smooth muscle cells in DGP rats was significantly higher than that in the normal control group, which suggested that apoptosis is involved in the development of DGP.