KRT1 and breast cancer: Other potential biomarkers for differentiating breast cancers and benign breast lesions include protein biomarkers such as the combination of epithelial membrane antigen and cytokeratin-1 (EMA and CK1; AUC of 0.9010), and developmental endothelial locus-1 (Del-1; AUC of 0.9200) [21,22].