Neurofibromatosis type 2 (NF2) is an autosomal-dominant tumor predisposition disorder caused by the inactivation of the NF2 tumor suppressor gene located on chromosome 22q12 and the functional loss of its protein product merlin (moesin-ezrin-radixin-like protein) [1]. The gene discussed is NF2; the disease is neurofibromatosis type 1.