SMARCA4 and pancreatic intraductal papillary-mucinous neoplasm: Characterization of SMARCA4-depleted IPMN-PDAC cells revealed the presence of repressive histone marks on the promoters of high-mobility group AT-hook 2 (Hmga2) gene, mediator of aggressive cancer phenotype, and other genes whose expression was reduced in IPMN-PDA [89].