ARID1B and cancer: Similar findings were observed in a previous study which concluded that ARID1B is the preferential gene required for the survival of ARID1A-mutant cancer cell lines and loss of ARID1B in ARID1A-deficient background destabilized SWI/SNF and impaired proliferation, suggesting that ARID1B might be a potential target in ARID1A-mutant cancers [95].