FOXO3 and breast cancer: The Kaplan–Meier (K–M) relapse-free survival (RFS) curve (log-rank test, p = 0.014) and the distant metastasis free survival (DMFS) curves (log-rank test, p = 0.00054) (Figure 5A,B) evidenced a better prognosis for Luminal A subtype breast cancer patients expressing high levels of FoxO3a mRNA.