Subtype-specific GWAS associations have so far been identified at 10q21.2 (ARID5B) associated with HD ALL, 10p14 (GATA3) for Philadelphia chromosome-like ALL, and 2q22.3 associated with ETV6-RUNX1-positive ALL7,9,12,18,19. Here, ARID5B is linked to acute lymphoblastic leukemia.