This patient also displayed polydactyly and syndactyly, two hallmark clinical features of humans with GLI3-Greigs cephalopolysyndactyly syndrome (GCPS), which corresponds to the loss of GLI3 transcriptional repression during limb development (Johnston et al., 2010; Al-Qattan et al., 2017). This evidence concerns the gene GLI3 and Greig cephalopolysyndactyly syndrome.