Reviewing previously reported GLI3 mutation subjects with GCPS or oral-facial-digital syndrome indicates that a small minority of these patients also display micropenis (Kroisel et al., 2001; Johnston et al., 2010), cryptorchidism (Kroisel et al., 2001; Johnston et al., 2010), or anosmia (Johnston et al., 2010). Here, GLI3 is linked to cryptorchidism.