Consistent with previous studies reporting that HGSOC tumours often exhibited alterations in one or more components of the RAS/PI3K/AKT signalling cascade, these analyses identified increased CN gains in multiple members of this pathway including: EGFR (qFisher = 4.6 × 10−3, qSpearman = 1.7 × 10−3), KRAS (qFisher = 1.7 × 10−2, qSpearman = 6.1 × 10−3), PIK3R2 (qFisher = 2.1 × 10−2, qSpearman = 2.4 × 10−2), and AKT2 (qFisher = 5.9 × 10−4, qSpearman = 2.1 × 10−10) (Fig. 2b). This evidence concerns the gene PIK3R2 and neoplasm.