PEBP1 and cancer: Little is known about the link between RKIP and inflammation in neoplastic context, however, given RKIP’s role in inflammatory processes through the modulation of signalling pathways, such as ERK/MAPK and NF-κB pathways, that are known to be widely deregulated in several malignancies (Figure 1 and Figure 2), it is possible that RKIP’s role in cancer can also be mediated by inflammation.