TNFSF11 and systemic lupus erythematosus: SLE patients on mofetil micofenolate (MMF, an immunosuppressant agent that inhibits inosine-5′-monophosphate dehydrogenase [IMPDH]) displayed normal osteoclastogenesis compared to SLE patient not taking MMF, showing a lower number of osteoclasts even if both populations exhibited similar serum RANKL levels [163].