MiR-205 is also a novel transcriptional target of p53 that inhibits cell proliferation involved in cell cycle progression, clonogenic potential in vitro and tumor growth in vivo, at least partially by targeting the two newly identified genes, E2F transcription factor 1 (E2F1) and laminin subunit gamma 1 (LAMC1) [152,153]. Here, E2F1 is linked to neoplasm.