ACADSB and 2-methylbutyryl-CoA dehydrogenase deficiency: Short/branched chain acyl-CoA dehydrogenase (SBCAD) deficiency is a genetic disorder (ACADSB gene) which can manifest as symptomatic in a small subgroup of patients (approx. 10%) with neurological symptoms, including developmental delay, hypotonia, and autism, having been reported [40].