GHRL and posterior cortical atrophy: Therefore, this report demonstrates that GOAT plays an pathophysiological role in PCa, which, together with other elements of the ghrelin system that we have recently demonstrated that also have oncogenic potential and are activated by the GOAT enzyme (i.e., ghrelin and In1-ghrelin splicing variant) [8], might integrate a regulatory circuit that is altered in patients with PCa to promote the oncogenic capacity of PCa cells.