KLK3 and posterior cortical atrophy: Therefore, although no direct comparison between GOAT and other emerging and well-studied biomarkers [25,26] have been performed (inasmuch as different cohorts and approximations have been used), these results suggest that GOAT could represent a novel and valuable complement for the PSA as non-invasive diagnostic biomarker to diagnose PCa (and/or SigPCa), especially in patients with PSA ranging from 3 to 10 ng/mL.