In this sense, our group has recently demonstrated that GOAT, an enzyme involved in the acylation and activation of ghrelin and, likely, other components of this hormonal axis (e.g., In1-ghrelin, In2c-ghrelin) [9], are overexpressed in PCa tissues, but most importantly, secreted by PCa cells [12]. The gene discussed is MBOAT4; the disease is posterior cortical atrophy.