However, interestingly, MSCs from the dental sources evaluated presented the same capacity to reduce the proliferation of CD4+ and CD8+ populations, which indicates that any of the three sources of DT-MSCs would be appropriate for in vivo immunoregulatory applications against T-cells, which is important because they are effector cells in immunological diseases such as graft-versus-host disease. This evidence concerns the gene CD8A and graft versus host disease.