TFRC and infection: In consideration of the role of TfR1 in helping the cell entry of several viruses, including New World hemorrhagic fever arenavirus [32], hepatitis C virus (HCV) [33], and poliovirus [34], we questioned whether CiTfR1 helps the GCRV infection, thus GCRV coerces the expression of CiTfR1, which then promotes the intracellular iron accumulation.