Among these 408 DEGs identified, four genes (WAS, ROCK1, and two genes with unknown functions) and six genes (PIK3CA, ROCK1, MYL5, ARHGAP5, CLDN2, and one gene with unknown function) were enriched to the “pathogenic E. coli infection” and “leukocyte transendothelial migration” pathways, respectively (Figure 4C; Table S1 in Supplementary Materials). Here, CLDN2 is linked to escherichia coli infection.