The correlation with important therapeutic targets in BLCA, including epidermal growth factor receptor (EGFR) (p = 7.73−31 for ANLN and p = 1.78−14 for TLE2), Erb-B2 receptor tyrosine kinase 2 (ERBB2) (p = 3.44−13 for ANLN and p = 1.96−43 for TLE2), fibroblast growth factor receptor 3 (FGFR3) (p = 6.52−9 for ANLN and p = 0.0016 for TLE2), and programmed death-ligand 1 (PD-L1) (p = 2.89−18 for ANLN and p = 1.07−18 for TLE2) were found to be significantly correlated with ANLN and TLE2 based on TCGA data (Table 4). Here, FGFR3 is linked to bladder transitional cell carcinoma.