Analysis of ANLN and TLE2 gene expression in association with copy-number alterations revealed a genetic alteration rate of 10% (41/407) for ANLN and 5% (21/407) for TLE2. Putative copy-number alterations including deep/shallow deletion, diploid, gain, and amplification were acquired from GISTIC (Genomic Identification of Significant Targets in Cancer). The gene discussed is TLE2; the disease is cancer.