The most common antibodies that are observed in MCTD patients are anti-U1-RNP (present in all our patients), anti-U1-70K (present in 76% of our patients), anti-U1-A (present in 84% of our patients), and anti-U1-C (present in 79% of our patients). The gene discussed is SNRNP70; the disease is mixed connective tissue disease.