We also observed that IFN-G rs1891493 AG might be a marker of anti-CCP presence in MCTD patients; furthermore, the IFN-G rs2069705 AG and IFN-G rs2069718 GA genotypes might be a marker of anti-Ro60 presence in MCTD patients (Table 8b). This evidence concerns the gene RO60 and mixed connective tissue disease.