We here show that OC and OA almost totally prevented the mRNA upregulation of IL-1β, MCP-1, CXCL-10 and, for OC only, M-CSF as well as MCP-1 protein secretion in inflamed adipocytes, thus highlighting the potential for these compounds to blunt adipocyte dysfunction and the associated pro-inflammatory cascade occurring during obesity. Here, CCL2 is linked to Obesity.