In addition, miR-19a-3p has been shown to inhibit breast cancer progression and metastasis by inducing a macrophage phenotype switch from M2 to M1 by targeting Fos-related antigen 1 (Fra-1), vascular endothelial growth factor (VEGF), and signal transducer and activator of transcription 3 (STAT3) [114]. This evidence concerns the gene STAT3 and breast cancer.