HNSCC patients with low expression of NETO2, CDK6, OLR1, and TGFBI have a better overall survival rate than HNSCC patients with high expression of these genes, while patients with low expression of NTF3 have a worse overall survival rate than those with high expression of NTF3. The gene discussed is TGFBI; the disease is head and neck squamous cell carcinoma.