APC, CDH1, GSTP1, RARB, RASSF1, MGMT, SOC51, CDH13, DAPK1, MLH1, PTEN, FHIT TIMP3 and VHL. These genes are frequently methylated in cervical cancer and associated with higher disease severity [55,56,57,58]. The gene discussed is APC; the disease is cervical cancer.