Although P-gp’s efflux function was inhibited, the ABCB1 mRNA levels were not significantly influenced by these triterpenoids under 72 h treatment, unlike in P-gp over-expressing cell line (ABCB1/Flp-InTM-293) or MDR cancer cell line (KB/VIN) (Figure 1c,d). This evidence concerns the gene PGP and cancer.