Indeed, prolonged interactions between stromal TAM (mainly CD163+ CD206+) and CD8 tumor-infiltrating lymphocytes (TILs) observed by dynamic imaging microscopy, are limiting CD8 T cell motility and their consecutive access to both human lung squamous cell carcinomas and mouse MMTV-PyMT tumors [39]. The gene discussed is CD8A; the disease is squamous cell lung carcinoma.