FMO5 and cancer: This is attributed to pro-oxidants changing their thiol/disulphide redox state which leads to diabetes mellitus and cancer or through the augmented action of either NAD(P)H oxidase leading to inflammatory oxidative conditions which is associated with chronic inflammation and atherosclerosis or through the action of xanthine oxidase-induced ROS formation which has been associated with reperfusion injury and ischemia [21].