A very recent multicentric study has indicated that numerous plasma proteins related to neuroinflammation, including three chemokines (eotaxin-1, MCP-1, and Macrophage Inflammatory Proteins (MIP) 1b (MIP-1b) and complement dysregulated proteins, could significantly and independently concur to differentiate MCI and AD patients from healthy controls. The gene discussed is CCL11; the disease is Alzheimer disease.