CCL2 and Alzheimer disease: Furthermore, a very recent international multicentric study, analyzing 53 inflammatory proteins in plasma of both AD and MCI, identified eotaxin-1 (higher in AD plasma vs. CTRL and MCI) and Monocyte Chemoattractant Protein-1 (MCP-1 or CCL2) (lower in AD plasma vs. CTRL and MCI), as potential inflammatory AD biomarkers [16].