While EAAT1 and EAAT2 display a predominant glial expression, EAAT3 appears to be neuron-specific, although EAAT3 expression has been also described in cells of glial origin, i.e., oligodendrocytes [2,21,22,23], rat C6 glioma cells and several human glioma cell models [2,24]. Here, SLC1A1 is linked to central nervous system cancer.