We can see that i) most of these pathways are observed in only a little fraction of the patients in COAD; ii) cell cycle pathway is enriched in most of patients in 12 cancer data sets (except COAD), demonstrating that cell cycle genes are regulated by TP53 in most of cancer patients; ii) Adherens junction pathway are enriched in most of patients (69.38%) for LUSC cancer data set while it is enriched in small number of patients (<50%) for other cancer data sets. The gene discussed is TP53; the disease is cancer.