IL6 and Hyponatremia: His favorable prognosis (no sequelae) is in accord with the study of Zhang et al.[3] In conclusion, in patients with encephalitis accompanied by hyponatremia, elevated IL-6 or urinary β2MG, and exacerbations such as sudden somnolence, delirium, confusion, and seizures, the possibility of secondary MERS, in addition to the progression of encephalitis, should be considered.