The background of this is that cells characterized by the markers CD34 or CD117 or CD133 under normal non‐leukemia conditions are able to divide and to generate normal mature blood cells, while in AML part of such cells are able to propagate leukemia (Beghini et al., 2012; Blair & Sutherland, 2000; Blair, Hogge, & Sutherland, 1998; Quek et al., 2016). This evidence concerns the gene PROM1 and acute myeloid leukemia.