The chain-like NeuN+ cells are reminiscent of differentiating GCPs migrating from the EGL to IGL during cerebellar development.8 Despite effectively driving tumor cells out of the cell cycle and inducing neuronal differentiation, radiation treatment failed to completely eliminate quiescent Sox2+ cells in Ptch1−/−p53R172P tumors (Figure 2F–H). Here, SOX2 is linked to neoplasm.