A later report by our group [14] presented further comprehensive mechanisms for LNCaP cell line survival rates modulated by PCA3. We found that LNCaP cells in which PCA3 was knocked-down induced the expression from 16 out of 84 tested tumor markers, including those involved in transcription control, cell signaling, angiogenesis, apoptosis, cell senescence, invasion, metastasis, cell adhesion and DNA damage repair [14] (Figure 2). Here, PCA3 is linked to neoplasm.