A study showed that miRNA-146a in MM-derived exosomes could be transmitted into BMSCs, resulting in the up-regulation of some specific cytokines and chemokines, such as CXCL1, IL-6, IL-8, IP10, MCP-1, and CCL-5, which leaded to the increased vitality and progression of MM cells. Here, CCL2 is linked to Miyoshi myopathy.