The expression of BCAR4 was higher in various tumor tissues than normal tissue or para-tumor tissue, including breast cancer 20-22, non-small-cell lung cancer 23-25, prostate cancer 26, osteosarcoma 27, 28, gastric cancer 29, cervical cancer 30 and colorectal cancer 31, 32. The gene discussed is BCAR4; the disease is osteosarcoma.